Crestor Information

Crestor, also known as rosuvastatin, is a drug in a class of medications called HMG-CoA reductase inhibitors, or statins, and works to inhibit the production of an enzyme in the liver which generates cholesterol. A factor that distinguishes Crestor (rosuvastatin) from the other five statins on the market is the drug's potential to cause kidney toxicity. AstraZeneca halted clinical trials of Crestor after reports of kidney damage and muscle weakness (early symptoms of rhabdomyolysis) in clinical trials in patients taking 80 milligrams of the drug per day. In the FDA review documents posted on the agency's web site before the Endocrinologic and Metabolic Drugs Advisory Committee it was noted "In contrast to currently approved statins, rosuvastatin was also associated with renal [kidney] findings not previously reported with other statins."

Crestor Label Changed Due to Safety Issues

Reports of rhabdomyolysis prompted European regulators to require AstraZeneca to change Crestor (rosuvastatin) product information and recommend a low initial dose.

US Consumer Group Seeks to Ban Crestor

Public Citizen filed a petition to ban Crestor with the FDA following reports of rhabdomyolysis and other adverse events, drug side effects, and drug interactions.

Crestor and Rhabdomyolysis

Rhabdomyolysis is the breakdown of muscle fibers resulting in the release of muscle fiber contents into the blood circulation. This process can be toxic to the kidneys and can result in myoglobinuria and kidney damage. Rhabdomyolysis and kidney problems are associated with the use of drugs in the statin class, including AstraZeneca's cholesterol-lowering drug Crestor.

Crestor and Legal Compensation

How to get legal compensation for a Crestor Injury or a Crestor Death.

Crestor Class Actions

Adverse events and side effects from using Crestor will prompt Crestor lawsuits. We believe an individual who suffers an injury caused by Crestor deserves an individual lawsuit.

Crestor Case Evaluation

Crestor News