Sodium-glucose cotransporter 2 inhibitors (SGLT-2 inhibitors) such as Invokana, Jardiance, and Farxiga have a higher risk of leg, feet, and toe amputations drug-class side effect when compared to older diabetes drugs such as sulfonylureas, metformin, and thiazolidinediones. This finding was … More
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Recent Articles
Actemra: FDA Evaluating Regulatory Action Due To Signs Of Serious Risk
Actemra is approved by the FDA for the treatment of several different medical conditions: Moderately to severely active rheumatoid arthritis in adult patients who have had an inadequate response to one or more Disease-Modifying Anti-Rheumatic Drugs (DMARDs); Giant Cell Arteritis (GCA) in … More
Current treatments and trials in malignant pleural mesothelioma
Objectives This article aims to review the evidence from recent clinical trials in mesothelioma, and to provide an overview of relevant clinical trials that are currently in progress. Results Since the original trial that demonstrated the efficacy of pemetrexed and cisplatin in mesothelioma, … More
Essure Birth Control Device Removed From Market By End Of Year 2018
Bayer recently announced that it will be pulling the Essure birth control device from the US market at the end of 2018. As for why there is this arguable “Essure recall”, we will start with Bayer’s spin on the situation. From this July 20, 2018 Washington Post news report, “Sales of Essure birth … More
Killed by a cuddle: Woman died after exposure to second-hand asbestos on husband’s overalls
Babcock International Ltd has been ordered to pay compensation to the children, grandchildren and siblings of Adrienne Sweeney, who lost her battle with mesothelioma – an extremely aggressive form of lung cancer – in August 2015 [after her exposures to second-hand asbestos years earlier]. The … More
Pradaxa Liver Injury: Label Changes Warning About This Increased Risk
We are watching to see whether the FDA and/or European drug regulators require a Pradaxa liver injury label change adding a new warning about an increased risk of acute liver failure and drug-induced hepatitis — like what was done in Japan last year and is being done now in Canada. In May 2018 … More