BACKGROUND: The median age at diagnosis for malignant pleural mesothelioma (MPM) is approximately 72 years. Elderly patients pose unique management challenges because of the increased risk of therapy-related toxicities and mortality. Because there are no high-volume retrospective studies, … More
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Recent Articles
Questions Raised About Whether Fournier’s Gangrene Is A Side Effect Of Farxiga, Invokana, And Jardiance
At the recent American Diabetes Association (ADA) Scientific Sessions there were reportedly questions raised about whether there is an increased risk of Fournier’s gangrene when using Farxiga as well as other SGLT2 inhibitor diabetes drugs such as Invokana and Jardiance. From this July 18, 2019 … More
Diagnostic Value of Biopsy Sampling in Predicting Histology in Patients With Diffuse Malignant Pleural Mesothelioma
BACKGROUND: The classification of diffuse malignant mesothelioma into epithelioid, biphasic, and sarcomatoid types is based on histologic patterns. The diagnosis is made on biopsies, and because of intratumoral heterogeneity, they may not be representative of the entire tumor. The number and volume … More
A Most Reckless Proposal — A Plan to Continue Asbestos Use in the United States
Each year, nearly 40,000 Americans die often painful, protracted deaths from diseases caused by asbestos. These deaths occur in firefighters, police officers, construction workers, miners, military veterans, shipyard workers, and maintenance workers whose exposures to asbestos are primarily … More
Xeljanz FDA Drug Safety Communication About Increased Risks of Blood Clots And Death
This Xeljanz FDA Drug Safety Communication was issued July 26, 2019: “FDA approves Boxed Warning about increased risk of blood clots and death with higher dose of arthritis and ulcerative colitis medicine tofacitinib (Xeljanz, Xeljanz XR)”. From that document we get the following … More
Will the FDA Ever Push the MiraLAX Pediatric Study?
Throughout our previous articles on the topic, we often discuss how the Children’s Hospital of Philadelphia (CHOP) has had a seemingly endless delay in their study on the effects of PEG 3350 (the main ingredient in MiraLAX) in children. A study that was originally supposed to be completed in 2015 … More